Aspirin and colorectal cancer chemoprevention
نویسندگان
چکیده
منابع مشابه
Chemoprevention of colorectal cancer by aspirin: a cost-effectiveness analysis.
BACKGROUND & AIMS The aim of the study is to compare the cost-effectiveness of aspirin and colonoscopy in the prevention of colorectal cancer. METHODS A Markov process is used to follow a hypothetical cohort of 100,000 subjects aged 50 years until death. Four strategies are compared: (1) no intervention, (2) colonoscopy once per 10 years and every 3 years in subjects with polyps, (3) chemopre...
متن کاملAspirin as a chemoprevention agent for colorectal cancer.
Colorectal cancer (CRC) is one of the leading causes of mortality in the western world. It is widely accepted that neoplasms such as colonic polyps are precursors to CRC formation; with the polyp-adenoma-carcinoma sequences well described in medical literature [1, 2]. It has been shown that Aspirin and other non-steroid anti-inflammatory drugs (NSAID) have a negative effect on polyp and cancer ...
متن کاملAspirin for cancer chemoprevention: still a headache?
Almost 7 million Americans, with the full blessing of their cardiologists, now take daily aspirin to prevent heart attacks, according to the Aspirin Foundation of America. But should we take aspirin to prevent cancer? Answers remain elusive, but the current consensus is: not yet, not even for colorectal cancer, where the strongest evidence exists. " We still have a long way to go to be certain ...
متن کاملAntiproliferative Effect of Aspirin on Colorectal Cancer Cell Line
Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) such as Aspirin may have anticancer properties, and can be effective as a novel strategy for the treatment of colorectal cancer (CRC). The aim of this study was to assess the cytotoxic effects of Aspirin drug in CRC cell lines compared with Oxaliplatin drug in vitro. Methods: Cell viability was assessed after treatment of SW742 and SW48...
متن کاملPost-study aspirin intake and factors motivating participation in a colorectal cancer chemoprevention trial.
We conducted an exploratory, cross-sectional study examining motivators for study participation and post-study aspirin intake in a chemoprevention trial. The parent clinical trial aimed to determine the optimal aspirin dose for colorectal cancer chemoprevention using prostaglandin E(2) as a mucosal biomarker. This trial was randomized and double-blinded in 60 subjects with prior sporadic colore...
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ژورنال
عنوان ژورنال: Mini-invasive Surgery
سال: 2018
ISSN: 2574-1225
DOI: 10.20517/2574-1225.2018.23